Total journals: 89   /   Total articles: 144
ID Journal Article title Publish date GSA BioProject
1 Plos One Diversity of the microbial community and cultivable protease-producing bacteria in the sediments of the Bohai Sea, Yellow Sea and South China Sea 2019-04 CRA000634 PRJCA000659
2 Cancer Medicine Prognostic implications of a molecular classifier derived from whole-exome sequencing in nasopharyngeal carcinoma 2019-04 CRA001397 PRJCA001219
3 Genome Biology Whole genomes and transcriptomes reveal adaptation and domestication of pistachio 2019-04 CRA000978 PRJCA000748
4 Poultry Science Rearing system causes changes of behavior, microbiome, and gene expression of chickens 2019-03 CRA000850
5 mSystems Core Microbiota in Agricultural Soils and Their Potential Associations with Nutrient Cycling 2019-03 CRA001238 PRJCA001121
6 MicrobiologyOpen Microbial community composition in alpine lake sediments from the Hengduan Mountains 2019-03 CRA001189 PRJCA001092
7 The ISME Journal Soil HONO emissions at high moisture content are driven by microbial nitrate reduction to nitrite: tackling the HONO puzzle 2019-03 CRA000459 PRJCA000532
8 Briefings in Bioinformatics Platform-independent approach for cancer detection from gene expression profiles of peripheral blood cells 2019-03 CRA001223 PRJCA001108
9 Poultry Science Relevance of the intestinal health-related pathways to broiler residual feed intake revealed by duodenal transcriptome profiling 2019-03 CRA000800 PRJCA000790
10 Cell Reports Expanded Expression Landscape and Prioritization of Circular RNAs in Mammals 2019-03 CRA000348 PRJCA000751
11 Biotechnology for Biofuels Kluyveromyces marxianus developing ethanol tolerance during adaptive evolution with significant improvements of multiple pathways 2019-03 CRA001456 PRJCA001291
12 Future oncology A breast one-patient panel of heterogeneous genomes reveals genetic alterations driving DCIS into invasive lesions 2019-03 CRA000203 PRJCA000368
13 Genes Genome-Wide Identification and Analysis of High-Copy-Number LTR Retrotransposons in Asian Pears 2019-02 CRA000269
14 Molecular Plant The HuangZaoSi maize genome provides insights into genomic variation and improvement history of maize 2019-02 CRA001441 PRJCA001247
15 Proceedings of the National Academy of Sciences of the United States of America Natural variation in the HAN1 gene confers chilling tolerance in rice and allowed adaptation to a temperate climate 2019-02 CRA000995
16 Environmental and Experimental Botany Discovery of unique single nucleotide polymorphisms in rice in response to high nighttime temperature stress using a hybrid sequencing strategy 2019-02 CRA001148 PRJCA001057
17 Microbiome Environmental filtering drives distinct continental atlases of soil archaea between dryland and wetland agricultural ecosystems 2019-02 CRA001282
18 Scientific Reports Comprehensive identification of the full-length transcripts and alternative splicing related to the secondary metabolism pathways in the tea plant (Camellia sinensis) 2019-02 CRA001188 PRJCA001073
19 Plos One The heterogeneity of plasma miRNA profiles in hepatocellular carcinoma patients and the exploration of diagnostic circulating miRNAs for hepatocellular carcinoma 2019-02 CRA000807 PRJCA000794
20 Journal of Agricultural and Food Chemistry Regulation of growth and flavonoids formation of tea plant (Camellia sinensis) by blue and green light 2019-02 CRA001119 PRJCA001034
21 BMC Biology Application of CRISPR-Cas12a temperature sensitivity for improved genome editing in rice, maize, and Arabidopsis 2019-01 CRA001068 PRJCA000992
22 Applied Microbiology and Biotechnology A genome-wide view of mutations in respiration-deficient mutants of Saccharomyces cerevisiae selected following carbon ionbeam irradiation 2019-01 CRA001107 PRJCA001026
23 Grass Science Research of photosynthesis and genomewide resequencing on a yellow‐leaf Lotus japonicus mutant induced by carbon ion beam irradiation 2019-01 CRA000577 PRJCA000631
24 Applied and Environmental Microbiology Resilience and Assemblage of Soil Microbiome in Response to Chemical Contamination Combined with Plant Growth 2019-01 CRA001242 PRJCA001123
25 National Science Review Ecological Principle Meets Cancer Treatment: Treating Children with Acute Myeloid Leukemia with Low-Dose Chemotherapy 2019-01 CRA000956 PRJCA000374
26 Planta Transcriptome analysis of 1- and 3-year-old Panax notoginseng roots and functional characterization of saponin biosynthetic genes DS and CYP716A47-like 2019-01 CRA001157 PRJCA001065
27 Molecular Biology and Evolution Genetic load and potential mutational meltdown in cancer cell populations 2019-01 CRA000224 PRJCA000406
28 Disease Models & Mechanisms An exonic splicing enhancer mutation in DUOX2 causes aberrant alternative splicing and severe congenital hypothyroidism in Bama pigs 2019-01 CRA001318 PRJCA001181
29 Proceedings of the National Academy of Sciences of the United States of America Genomic and transcriptomic investigations of the evolutionary transition from oviparity to viviparity 2018-12 CRA001096 PRJCA001024
30 International Journal of Molecular Sciences Distinct Patterns of PPARγ Promoter Usage, Lipid Degradation Activity, and Gene Expression in Subcutaneous Adipose Tissue of Lean and Obese Swine 2018-12 CRA001170 PRJCA001069
31 BMC Systems Biology Circular RNA expression profiles during the differentiation of mouse neural stem cells 2018-12 CRA000708 PRJCA000718
32 Neuroscience RNA-seq Analysis of the SCN1A-KO Model based on CRISPR/Cas9 Genome Editing Technology 2018-12 CRA000951 PRJCA000886
33 World Journal of Microbiology and Biotechnology Repair characteristics and time-dependent effects in Saccharomyces cerevisiae cells after X-ray irradiation 2018-12 CRA001216
34 Molecules Transcriptomic Insight into Terpenoid Biosynthesis and Functional Characterization of Three Diterpene Synthases in Scutellaria barbata 2018-11 CRA001174 PRJCA001076
35 Protein & Cell Tongue coating microbiome as a potential biomarker for gastritis including precancerous cascade 2018-11 CRA000643 PRJCA000663
36 Molecular & Cellular Proteomics Characterization of proteome variation during modern maize breeding 2018-11 CRA000334 PRJCA000509
37 Journal of Animal Science Transcriptome changes provide genetic insights into the effects of rearing systems on chicken welfare and product quality 2018-11 CRA000838
38 Journal of Integrative Plant Biology Genome‐wide screening of long non‐coding RNAs involved in rubber biosynthesis in Eucommia ulmoides 2018-11 CRA000720 PRJCA000726
39 Molecular Biology Reports Development and application of EST-SSRs markers for analysis of genetic diversity in erect milkvetch (Astragalus adsurgens Pall.) 2018-11 CRA001062 PRJCA000988
40 BMC Genomics Improved Macaca fascicularis gene annotation reveals evolution of gene expression profiles in multiple tissues 2018-11 CRA000680 PRJCA000684
41 Microorganisms Low Concentration of Antibiotics Modulates Gut Microbiota at Different Levels in Pre-Weaning Dairy Calves 2018-11 CRA000901 PRJCA000813
42 Agronomy Comparative Analysis of the Transcriptional Response of Tolerant and Sensitive Wheat Genotypes to Drought Stress in Field Conditions 2018-11 CRA001148 PRJCA001057
43 Journal of Cellular and Molecular Medicine Whole exome sequencing identified a novel DAG1 mutation in a patient with rare, mild and late age of onset muscular dystrophy-dystroglycanopathy 2018-11 CRA000997 PRJCA000917
44 Journal of Molecular Cell Biology Hunt for the tipping point during endocrine resistance process in breast cancer by dynamic network biomarkers 2018-11 CRA000580 PRJCA000628
45 Genome Biology Holo-Seq: single-cell sequencing of holo-transcriptome 2018-10 CRA001133
46 The Plant Cell Sweet Sorghum Originated through Selection of Dry, a Plant-Specific NAC Transcription Factor Gene 2018-10 CRA000611 PRJCA000637
47 Genome Research Transcriptome evidence reveals enhanced autophagy-lysosomal function in centenarians 2018-10 CRA000515 PRJCA000568
48 Cell Research METTL3-mediated N6-methyladenosine mRNA modification enhances long-term memory consolidation 2018-10 CRA001077 PRJCA001008
49 Emerging Microbes & Infections Zika virus shedding in the stool and infection through the anorectal mucosa in mice 2018-10 CRA000783 PRJCA000776
50 Food Research International An integrated metagenomic/metaproteomic investigation of microbiota in dajiang-meju, a traditional fermented soybean product in Northeast China 2018-10 CRA001049 PRJCA000974
51 Wiley Aquaculture Research Dietary citric acid supplementation alleviates soybean meal‐induced intestinal oxidative damage and micro‐ecological imbalance in juvenile turbot, Scophthalmus maximus L 2018-10 CRA000703 PRJCA000703
52 The Journal of Clinical Investigation Chromatin regulator Asxl1 loss and Nf1 halpoinsufficiency cooperate to accelerate myeloid malignancy 2018-09 CRA000668
53 New Phytologist DNA methylation dynamics during the interaction of wheat progenitor Aegilops tauschii with the obligate biotrophic fungus Blumeria graminis f. sp. tritici 2018-09 CRA000898
54 Nature Communications Ring synthetic chromosome V SCRaMbLE 2018-09 CRA000963 PRJCA000897
55 PeerJ Exome sequencing study of 20 patients with high myopia 2018-09 CRA000769
56 Plant, Cell & Environment Meta-analysis and transcriptome profiling reveal hub genes for soybean seed storage composition during seed development 2018-09 CRA000592 PRJCA000523
57 Genome Research Death of new microRNA genes in Drosophila via gradual loss of fitness advantages 2018-09 CRA000857 PRJCA000812
58 Genome Biology DNA methylation footprints during soybean domestication and improvement 2018-09 CRA000747 PRJCA000740
59 Genome Biology Reduced intrinsic DNA curvature leads to increased mutation rate 2018-09 CRA000570 PRJCA000622
60 Plos One Transcriptome and metabolome analysis reveal candidate genes and biochemicals involved in tea geometrid defense in Camellia sinensis 2018-08 CRA000859 PRJCA000810
61 International Journal of Molecular Sciences Substantial Epigenetic Variation Causing Flower Color Chimerism in the Ornamental Tree Prunus mume Revealed by Single Base Resolution Methylome Detection and Transcriptome Sequencing 2018-08 CRA000731 PRJCA000732
62 Wiley MicrobiologyOpen Comparative metagenomics of the gut microbiota in wild greylag geese (Anser anser) and ruddy shelducks (Tadorna ferruginea) 2018-08 CRA000822
63 BMC Microbiology Transcriptome analysis of Valsa mali reveals its response mechanism to the biocontrol actinomycete Saccharothrix yanglingensis Hhs.015 2018-08 CRA000693 PRJCA000699
64 International Journal of Rheumatic Diseases Targeted capture sequencing identifies novel genetic variations in Chinese patients with idiopathic inflammatory myopathies 2018-08 CRA000871 PRJCA000807
65 Proceedings of the National Academy of Sciences of the United States of America Scleral hypoxia is a target for myopia control 2018-07 CRA000775 PRJCA000717
66 PeerJ Biases during DNA extraction affect characterization of the microbiota associated with larvae of the Pacific white shrimp, Litopenaeus vannamei 2018-07 CRA000198 PRJCA000363
67 National Science Review Structural variation during dog domestication: insights from gray wolf and dhole genomes 2018-07 CRA000955
68 Nature Communications An intercross population study reveals genes associated with body size and plumage color in ducks 2018-07 CRA000651 PRJCA000647
69 European Journal of Human Genetics Paternal origin of Paleo-Indians in Siberia: insights from Y-chromosome sequences. 2018-07 CRA000236
70 Genomics, Proteomics & Bioinformatics 5-Hydroxymethylome in Circulating Cell-free DNA as A Potential Biomarker for Non-small-cell Lung Cancer 2018-07 CRA000872 PRJCA000816
71 Science China Life Sciences De novo assembly of a Chinese soybean genome 2018-07 CRA001007 PRJCA000902
72 Zoological Research Identification and characterization of short tandem repeats in the Tibetan macaque genome based on resequencing data 2018-07 CRA000789 PRJCA000782
73 BioRxiv Overdosage of balanced protein complexes reduces proliferation rate in aneuploid cells 2018-07 CRA000490 PRJCA000491
74 Nucleic Acids Research Genome wide analyses uncover allele-specific RNA editing in human and mouse 2018-07 CRA000575 PRJCA000627
75 Genome Biology A large-scale whole-genome sequencing analysis reveals highly specific genome editing by both Cas9 and Cpf1 (Cas12a) nucleases in rice 2018-07 CRA000633 PRJCA000656
76 Frontiers in Plant Science Comparative Genomics and Phylogenetic Analysis Revealed the Chloroplast Genome Variation and Interspecific Relationships of Corylus (Betulaceae) Species 2018-07 CRA000795 PRJCA000786
77 Frontiers in Cellular and Infection Microbiology Detection of Pulmonary Infectious Pathogens From Lung Biopsy Tissues by Metagenomic Next-Generation Sequencing 2018-06 CRA000937 PRJCA000880
78 BioRxiv Assembly of chromosome-scale contigs by efficiently resolving repetitive sequences with long reads 2018-06 CRA000161 PRJCA000313
79 Oncotarget The landscape of somatic mutation in sporadic Chinese colorectal cancer. 2018-06 CRA000626 PRJCA000610
80 Cell Stem Cell Single-Cell RNA-Seq Reveals Dynamic Early Embryonic-like Programs during Chemical Reprogramming 2018-06 CRA000932 PRJCA000878
81 The Plant Cell A Core Regulatory Pathway Controlling Rice Tiller Angle Mediated by the LAZY1-dependent Asymmetric Distribution of Auxin. 2018-06 CRA000335 PRJCA000470
82 Genome Biology RNA m6A methylation participates in regulation of postnatal development of the mouse cerebellum. 2018-05 CRA000472 PRJCA000543
83 Nature Communications In vitro DNA SCRaMbLE 2018-05 CRA000752 PRJCA000757
84 Frontiers in Microbiology Tachyplesin Causes Membrane Instability That Kills Multidrug-Resistant Bacteria by Inhibiting the 3-Ketoacyl Carrier Protein Reductase FabG. 2018-05 CRA000801 PRJCA000788
85 Proceedings of the National Academy of Sciences of the United States of America Selection and environmental adaptation along a path to speciation in the Tibetan frog Nanorana parkeri 2018-05 CRA000918 PRJCA000443
86 Nature Genome sequence of the progenitor of wheat A subgenome Triticum urartu. 2018-05 CRA000205 PRJCA000369
87 Nature Communications Precise control of SCRaMbLE in synthetic haploid and diploid yeast. 2018-05 CRA000723 PRJCA000730
88 BMC Genomics Direct measurement of pervasive weak repression by microRNAs and their role at the network level. 2018-05 CRA000921 PRJCA000381
89 BioRxiv DNA local structure decreases mutation rates 2018-04 CRA000570 PRJCA000622
90 Frontiers in Genetics Whole Exome Sequencing Identified a Novel Heterozygous Mutation in HMBS Gene in a Chinese Patient With Acute Intermittent Porphyria With Rare Type of Mild Anemia. 2018-04 CRA000851 PRJCA000809
91 Industrial Crops and Products Identification and characterization of long non-coding RNAs involved in the formation and development of poplar adventitious roots 2018-04 CRA000744 PRJCA000745
92 Journal of Molecular Cell Biology MeCP2 deficiency promotes cell reprogramming by stimulating IGF1/AKT/mTOR signaling and activating ribosomal protein-mediated cell cycle gene translation. 2018-03 CRA000764 PRJCA000763
93 Cell Chromatin Accessibility Landscape in Human Early Embryos and Its Association with Evolution. 2018-03 CRA000297 PRJCA000484
94 Journal of Human Genetics The uncertainty of population relationship and divergence time inferred by the multiple sequentially Markovian coalescent model. 2018-03 CRA000539 PRJCA000600
95 Zoological Research Complete mitochondrial genome of the Thai Red Junglefowl (Gallus gallus) and phylogenetic analysis. 2018-03 CRA000143 PRJCA000287
96 Frontiers in Microbiology Analyzing AbrB-Knockout Effects through Genome and Transcriptome Sequencing of Bacillus licheniformis DW2 2018-02 CRA000557 PRJCA000615
97 Animal Genetics Genomic variation in Pekin duck populations developed in three different countries as revealed by whole-genome data. 2018-02 CRA000523 PRJCA000547
98 Cancer Research Multiregional Sequencing Reveals Genomic Alterations and Clonal Dynamics in Primary Malignant Melanoma of the Esophagus. 2018-01 CRA000346 PRJCA000536
99 Frontiers in Plant Science Constitutive Expression of miR408 Improves Biomass and Seed Yield in Arabidopsis 2018-01 CRA000553 PRJCA000613
100 BMC Genomics High-sensitivity HLA typing by Saturated Tiling Capture Sequencing (STC-Seq). 2018-01 CRA000645 PRJCA000665
101 Cell Death and Differentiation TMCO1 is essential for ovarian follicle development by regulating ER Ca2+store of granulosa cells. 2018-01 CRA000296 PRJCA000482
102 PLoS Pathog A role for small RNA in regulating innate immunity during plant growth. 2018-01 CRA000618 PRJCA000650
103 Plos One Comparative analysis of miRNA and mRNA abundance in determinate cucumber by high-throughput sequencing 2018-01 CRA000559 PRJCA000617
104 Schizophrenia Research Analysis of gut microbiota diversity and auxiliary diagnosis as a biomarker in patients with schizophrenia: A cross-sectional study. 2018-01 CRA000653 PRJCA000673
105 Molecular Biology and Evolution Out of Southern East Asia of the Brown Rat Revealed by Large-Scale Genome Sequencing 2018-01 CRA000345 PRJCA000251
106 European Journal of Human Genetics Whole-sequence analysis indicates that the Y chromosome C2*-Star Cluster traces back to ordinary Mongols, rather than Genghis Khan. 2018-01 CRA000236 PRJCA000420
107 Molecular Genetics and Genomics Whole sequence analysis indicates a recent southern origin of Mongolian Y-chromosome C2c1a1a1-M407. 2017-12 CRA000194 PRJCA000359
108 GigaScience Draft genome of the Marco Polo Sheep (Ovis ammon polii). 2017-12 CRA000260 PRJCA000449
109 Plos One Genomic sequencing identifies a few mutations driving the independent origin of primary liver tumors in a chronic hepatitis murine model 2017-11 CRA000681
110 European Journal of Human Genetics Mitochondrial genomes uncover the maternal history of the Pamir populations. 2017-11 CRA000330 PRJCA000486
111 Cell Research Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia. 2017-11 CRA000096 PRJCA000224
112 Genes & Genomics Comparative transcriptome analysis of tube feet of different colors in the sea urchin Strongylocentrotus intermedius 2017-11 CRA000134 PRJCA000276
113 Proceedings of the National Academy of Sciences of the United States of America Mediator subunit MED25 links the jasmonate receptor to transcriptionally active chromatin. 2017-10 CRA000278 PRJCA000475
114 Journal of Human Genetics Phylogeny of Y-chromosome haplogroup C3b-F1756, an important paternal lineage in Altaic-speaking populations. 2017-10 CRA000235 PRJCA000419
115 Journal of Genetics and Genomics Genome wide abnormal DNA methylome of human blastocyst in assisted reproductive technology. 2017-10 CRA000114 PRJCA000248
116 Genomics, Proteomics & Bioinformatics Ribosome Profiling Reveals Genome-wide Cellular Translational Regulation upon Heat Stress in Escherichia coli. 2017-10 CRA000347 PRJCA000608
117 Molecular Plant The Tartary Buckwheat Genome Provides Insights into Rutin Biosynthesis and Abiotic Stress Tolerance. 2017-09 CRA000226
118 Proceedings of the Royal Society B: Biological Sciences Seasonal variation in nutrient utilization shapes gut microbiome structure and function in wild giant pandas. 2017-09 CRA000202 PRJCA000366
119 Nature m6A modulates haematopoietic stem and progenitor cell specification 2017-09 CRA000275 PRJCA000469
120 The Plant Cell MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. 2017-08 CRA000249
121 Epigenetics Mouse olfactory bulb methylome and hydroxymethylome maps reveal noncanonical active turnover of DNA methylation 2017-08 CRA000145 PRJCA000310
122 Front Cell Infect Microbiol Splenic microRNA Expression Profiles and Integration Analyses Involved in Host Responses to Salmonella enteritidis Infection in Chickens. 2017-08 CRA000315 PRJCA000485
123 Molecular psychiatry Targeted sequencing and functional analysis reveal brain-size-related genes and their networks in autism spectrum disorders. 2017-07 CRA000220 PRJCA000393
124 Cell 3D Chromatin Structures of Mature Gametes and Structural Reprogramming during Mammalian Embryogenesis. 2017-07 CRA000108 PRJCA000241
125 Scientific Reports A Comprehensive Mouse Transcriptomic BodyMap by RNA-seq 2017-06 CRA000240 PRJCA000427
126 Nature Communications Loss of Asxl2 leads to myeloid malignancies in mice. 2017-06 CRA000122 PRJCA000259
127 Genes Genome-Wide Identification and Characterization of Salinity Stress-Responsive miRNAs in Wild Emmer Wheat (Triticum turgidum ssp. dicoccoides). 2017-06 CRA000238 PRJCA000426
128 Theranostics Microvesicles as Potential Biomarkers for the Identification of Senescence in Human Mesenchymal Stem Cells. 2017-06 CRA000160 PRJCA000325
129 BioRxiv Draft genome of the Reindeer (Rangifer tarandus) 2017-06 CRA000262 PRJCA000451
130 Genome Biology Differentiated demographic histories and local adaptations between Sherpas and Tibetans. 2017-06 CRA000112 PRJCA000246
131 Cell Research 5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. 2017-05 CRA000162 PRJCA000315
132 Frontiers in Cellular and Infection Microbiology The Bioinformatics Analysis of Comparative Genomics of Mycobacterium tuberculosis Complex (MTBC) Provides Insight into Dissimilarities between Intraspecific Groups Differing in Host Association, Virulence, and Epitope Diversity. 2017-03 CRA000155 PRJCA000307
133 BMC Genomics Global transcriptome analysis of Huperzia serrata and identification of critical genes involved in the biosynthesis of huperzine A. 2017-03 CRA000188 PRJCA000351
134 Genome Research LTR-mediated retroposition as a mechanism of RNA-based duplication in metazoans 2016-12 CRA000139
135 Cell Stem Cell Zika Virus Disrupts Neural Progenitor Development and Leads to Microcephaly in Mice 2016-11 CRA000128 PRJCA000267
136 Scientific Reports Fish gut-liver immunity during homeostasis or inflammation revealed by integrative transcriptome and proteome studies. 2016-11 CRA000085 PRJCA000207
137 Plos One Complete Sequence and Analysis of Coconut Palm (Cocos nucifera) Mitochondrial Genome. 2016-10 CRA000123 PRJCA000261
138 Proceedings of the National Academy of Sciences of the United States of America Integrated analysis of phenome, genome, and transcriptome of hybrid rice uncovered multiple heterosis-related loci for yield increase. 2016-10 CRA000026 PRJCA000131
139 American Journal of Human Genetics Ancestral Origins and Genetic History of Tibetan Highlanders. 2016-09 CRA000112 PRJCA000246
140 Current Biology Convergent Evolution of Rumen Microbiomes in High-Altitude Mammals. 2016-07 CRA000018
141 Stem Cell Reports Loss of Asxl1 Alters Self-Renewal and Cell Fate of Bone Marrow Stromal Cell, Leading to Bohring-Opitz-like Syndrome in Mice. 2016-06 CRA000104 PRJCA000236
142 Journal of Cell Science ESCRT-0 complex modulates Rbf-mutant cell survival by regulating Rhomboid endosomal trafficking and EGFR signaling. 2016-05 CRA000094 PRJCA000222
143 Cell Research Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer. 2016-01 CRA000010 PRJCA000102
144 Proceedings of the National Academy of Sciences of the United States of America Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution. 2015-11 CRA000004 PRJCA000091