BioProject > Project detail information
Identifier PRJCA000416
Title A Comparative Transcriptomic Analysis of Uveal Melanoma and Normal Uveal Melanocyte
Project data type Transcriptome or Gene expression
Organism Homo sapiens
Relevance Medical
Description Uveal melanoma is the most common primary intraocular tumor in adults in western countries. It is associated with very severe visual morbidity and may lead to distant metastases even after successful treatment of the primary tumor. In order to gain better insight into molecular mechanisms related to tumorigenesis and metastasis of uveal melanoma, we used next-generation sequencing technology (SOLiD, Life Technologies) to acquire global transcriptome alteration between posterior uveal melanoma cells and normal uveal melanocyte.We have identified a large number of potentially interesting genes for biological investigation of uveal melanoma. The expression profiling also provides useful resources for other functional genomic and transcriptome studies.
Project type information
Sample scope Material Capture Methodology Objective
Monoisolate Transcriptome Whole Sequencing Raw Sequence Reads
Target information
Strain, breed, cultivar Isolate name or label Description
Title Pubmed ID Doi Journal Year
A comparative transcriptomic analysis of uveal melanoma and normal uveal melanocyte. 21305041 10.1371/journal.pone.0016516 PloS one 2011
Release date 2017-04-11
Project data Samples:2
Availability FTP download
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Submitter gl  wang;  cas
Submitted date 2017-04-11